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DOV-216,303 Free Base, MedChemExpress

Product Code. 16439987
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5 mg
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16439987 5 mg 5mg
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Product Code. 16439987 Supplier Medchem Express Supplier No. HY18332C

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Description

MedChemExpress DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats.

DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats.

Specifications

Chemical Name or Material DOV-216,303 Free Base
CAS 66504-40-3
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C11H11Cl2N
Quantity 5 mg
Solubility Information DMSO : ≥ 125 mg/mL (547.96 mM) ∣Ethanol : 100 mg/mL (438.37 mM; Need ultrasonic)
SMILES ClC1=C(Cl)C=C(C=C1)C12CC1CNC2
Molecular Weight (g/mol) 228.12
Formula Weight 228.12
Percent Purity 98.77%
Grade Research
Physical Form Oil
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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