YPEL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16894554	Proteintech 15403-1-AP-20UL	20 μL
16884554	Proteintech 15403-1-AP-150UL	150 μL

Description

15403-1-AP was raised against full length of YPEL3 protein (1-119 aa); it can recognize YPEL1-4.

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Specifications

• Antigen: YPEL3
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P61236, P61237
• Gene ID (Entrez): 293491, 66090, 83719
• Immunogen: YPEL3 Fusion Protein Ag7626
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: YPEL3

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Protein yippee like 3, yippee like 3 (Drosophila), YPEL3
• Gene Symbols: Ypel3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody