YPEL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15403-1-AP-20UL

Product Code. 16894554

Description

15403-1-AP was raised against full length of YPEL3 protein (1-119 aa); it can recognize YPEL1-4.

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Specifications

• Antigen: YPEL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: YPEL3
• Gene Alias: Protein yippee like 3, yippee like 3 (Drosophila), YPEL3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293491, 66090, 83719
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P61236, P61237
• Gene Symbols: Ypel3
• Immunogen: YPEL3 Fusion Protein Ag7626
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG