Invitrogen™ VNN1 Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17949952	Invitrogen™ MA551160	20 μL
17980573	Invitrogen™ MA551159	200 μL

Description

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.

Specifications

• Antigen: VNN1
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: HDLCQ8; Pantetheinase; pantetheine hydrolase; Tiff66; V-1; vanin 1; Vanin1; vanin-1; vannin 1; vascular non-inflammatory molecule 1; VNN1
• Gene Symbols: VNN1
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: VNN1

• Clone: C2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Pig
• Gene Accession No.: O95497, Q9BDJ5
• Gene ID (Entrez): 397246, 8876
• Immunogen: Recombinant Human VNN1 protein, Gln22-Gly491 (Accession #O95497).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.