VAMP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16897313	Proteintech 10738-1-AP-20UL	20 μL
16887313	Proteintech 10738-1-AP-150UL	150 μL

Description

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer′s disease, VAMP levels of all isoforms appear to be significantly lowered.

Specifications

• Antigen: VAMP4
• Applications: Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: O70480, O75379
• Gene ID (Entrez): 364033, 53330, 8674
• Immunogen: VAMP4 Fusion Protein Ag1090
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: VAMP4

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: VAMP 4, VAMP24, VAMP4
• Gene Symbols: Vamp4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody