UCH-L1/PGP9.5 Antibody (UCHL1/775), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18168858	Novus Biologicals NBP2-44795-0.02MG	0.02 mg
18154158	Novus Biologicals NBP2-44795-0.1MG	0.1 mg

Description

Ensure accurate, reproducible results in Western Blot, Immunohistochemistry (Paraffin)

UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Rat samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: UCH-L1/PGP9.5
• Concentration: 0.2mg/mL
• Applications: Western Blot, Immunohistochemistry (Paraffin), SDS-Page
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
• Gene Symbols: UCHL1
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

• Clone: UCHL1/775
• Dilution: Western Blot 0.5 - 1.0 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Rat
• Gene Accession No.: P09936
• Gene ID (Entrez): 7345
• Immunogen: Recombinant human UCHL1 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

For Research Use Only