TXNRD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11117-1-AP-20UL

Product Code. 16887973

Description

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Specifications

• Antigen: TXNRD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TXNRD1
• Gene Alias: GRIM 12, GRIM12, KDRF, thioredoxin reductase 1, Thioredoxin reductase TR1, TR, TR1, TRXR1, TXNR, TXNRD1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50493, 58819, 7296
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation, Flow Cytometry
• Concentration: 0.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: O89049, Q16881, Q9JMH6
• Gene Symbols: Txnrd1
• Immunogen: TXNRD1 Fusion Protein Ag1618
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Human, Mouse
• Product Type: Antibody
• Isotype: IgG