Invitrogen™ TMEM43 Recombinant Rabbit Monoclonal Antibody (24GB2325)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557796

Product Code. 30276027

Description

TMEM43 Recombinant Monoclonal Antibody for Western Blot, Flow

This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Specifications

• Antigen: TMEM43
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: TMEM43
• Gene Alias: 1200015A22Rik; ARVC5; ARVD5; EDMD7; LUMA; Protein LUMA; Tmem43; Transmembrane protein 43; UNQ2564/PRO6244
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 362401, 74122, 79188
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB2325
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5XIP9, Q9BTV4, Q9DBS1
• Gene Symbols: TMEM43
• Immunogen: A synthesized peptide derived from human TMEM43 (aa 100-135).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG