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Thermo Scientific™ Tango™ MCHR2-bla U2OS Cells

Product Code. 10358534
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Quantity:
8 x 106 cells/vial
Unit Size:
Each
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Product Code. 10358534

Brand: Thermo Scientific™ K1836

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Description

The Tango™ MCHR2-bla U2OS cells contain the human Melanin-concentrating hormone receptor 2 (MCHR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

The Tango™ MCHR2-bla U2OS cells contain the human Melanin-concentrating hormone receptor 2 (MCHR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ MCHR2-bla U2OS cells are functionally validated for Z' and EC50 concentrations of I-TAC (CXCL11). In addition, Tango™ MCHR2-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_032503.2
Assay Entry Cell-based beta-arrestin recruitment
Cell State Dividing Cells
Content And Storage LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ MCHR2-bla U2OS cells
• Tango™ MCHR2-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ MCHR2-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Cytoplasmic Tail Tail from AVPR2 GPCR
Description Tango™ MCHR2-bla U2OS Cells, 8 x 106 Cells, U2OS Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol MCHR2
Human Protein Class G-Protein Coupled Receptor (GPCR)
Includes Tango™ MCHR2-bla U2OS cells (LiveBLAzer™-FRET B/G loading kit, solution D and other materials are required separately; please refer to the protocol). Includes: Tango™ MCHR2-bla U2OS cells, Tango™ MCHR2-bla U2OS assay protocol, certificate of analysis
Population Status Single Cell Clone Origin
Product Line GeneBLAzer, Tango
Quantity 8 x 106 cells/vial
Readout End Point
Sample Type U2OS
Shipping Condition Room Temperature
Target Entry GPR145, MCHR2
Type U2OS Cell
Cell Line U2OS
System Type Tango™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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