Invitrogen™ SYNE3 Recombinant Rabbit Monoclonal Antibody (23GB4670), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553785

Product Code. 30089606

Description

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt].

Specifications

• Antigen: SYNE3
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: SYNE3
• Gene Alias: C14orf139; C14orf49; KASH domain-containing protein 3; KASH3; LINC00341; Nesp3; nesprin-3; NET53; Nuclear envelope spectrin repeat protein 3; RGD1304563; spectrin repeat containing nuclear envelope family member 3; spectrin repeat containing, nuclear envelope family member 3; SYNE3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 161176
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB4670
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6ZMZ3
• Gene Symbols: SYNE3
• Immunogen: A synthesized peptide derived from human Nesprin3 (750-935AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG