Invitrogen™ Synapsin 1 Recombinant Rabbit Monoclonal Antibody (3I9R10)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30283697	Invitrogen™ MA558171	20 μL
30284608	Invitrogen™ MA558172	100 μL

Description

Immunogen sequence: EDKQLIVELV VNKMAQALPR QRQRDASPGR GSHGQTPSPG ALPLGRQTSQ QPAGPPAQQR PPPQGGPPQP GPGPQRQGPP LQQRPPPQGQ QHLSGLGPPA.

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Synapsin 1
• Concentration: 0.57 mg/mL
• Applications: ELISA, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O88935, P09951
• Gene ID (Entrez): 20964, 24949
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 401-500 of human Synapsin-1 (NP_008881.2).
• Product Type: Antibody

• Clone: 3I9R10
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse, Rat
• Gene: SYN1
• Gene Alias: Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
• Gene Symbols: SYN1
• Primary or Secondary: Primary
• Purification Method: Protein A