Invitrogen™ Synapsin 1 Recombinant Rabbit Monoclonal Antibody (3I9R10)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA558171

Product Code. 30283697

Description

Immunogen sequence: EDKQLIVELV VNKMAQALPR QRQRDASPGR GSHGQTPSPG ALPLGRQTSQ QPAGPPAQQR PPPQGGPPQP GPGPQRQGPP LQQRPPPQGQ QHLSGLGPPA.

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Synapsin 1
• Classification: Recombinant Monoclonal
• Concentration: 0.57 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O88935, P09951
• Gene Symbols: SYN1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 401-500 of human Synapsin-1 (NP_008881.2).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: 3I9R10
• Conjugate: Unconjugated
• Gene: SYN1
• Gene Alias: Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20964, 24949
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid