Invitrogen™ STAT5 beta Recombinant Rabbit Monoclonal Antibody (24GB2110)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30276125	Invitrogen™ MA557740	100 μL
30275140	Invitrogen™ MA557741	20 μL

Description

STAT5 beta Recombinant Monoclonal Antibody for Western Blot, Flow

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Specifications

• Antigen: STAT5 beta
• Concentration: 0.53 mg/mL
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P42232, P51692, P52632
• Gene ID (Entrez): 20851, 25126, 6777
• Immunogen: A synthesized peptide derived from human STAT5B (aa 500-787).
• Product Type: Antibody

• Clone: 24GB2110
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: Stat5b
• Gene Alias: LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
• Gene Symbols: Stat5b
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography