Invitrogen™ SPINK5 Recombinant Rabbit Monoclonal Antibody (23GB4180), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553705

Product Code. 30088682

Description

Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.

Specifications

• Antigen: SPINK5
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: SPINK5
• Gene Alias: 2310065D10Rik; AV238912; Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665; ISK5; LEKT1; LEKTI; LETK1; LETKI; lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor; Netherton syndrome; NETS; NS; serine peptidase inhibitor, Kazal type 5; serine protease inhibitor Kazal-type 5; serine protease inhibitor, Kazal type 5; SPINK5; VAKT1; VAKTI
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11005, 361319, 72432
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB4180
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9NQ38
• Gene Symbols: SPINK5
• Immunogen: A synthesized peptide derived from human SPINK5/LEKTI (150-200AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG