Invitrogen™ SPINK5 Monoclonal Antibody (C10), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17634026	Invitrogen™ MA543567	20 μL
17624026	Invitrogen™ MA543566	100 μL

Description

Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.

Specifications

• Antigen: SPINK5
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Alias: 2310065D10Rik; AV238912; Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665; ISK5; LEKT1; LEKTI; LETK1; LETKI; lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor; Netherton syndrome; NETS; NS; serine peptidase inhibitor, Kazal type 5; serine protease inhibitor Kazal-type 5; serine protease inhibitor, Kazal type 5; SPINK5; VAKT1; VAKTI
• Gene Symbols: SPINK5
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Product Type: Antibody

• Clone: C10
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q9NQ38
• Gene ID (Entrez): 11005
• Immunogen: Gly699-Ser976 (Accession Q9NQ38), with N-terminal His Tag.
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Gene: SPINK5