Invitrogen™ SPINK5 Monoclonal Antibody (C10), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA543566

Product Code. 17624026

Description

Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.

Specifications

• Antigen: SPINK5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q9NQ38
• Gene Symbols: SPINK5
• Immunogen: Gly699-Ser976 (Accession Q9NQ38), with N-terminal His Tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: C10
• Conjugate: Unconjugated
• Gene: SPINK5
• Gene Alias: 2310065D10Rik; AV238912; Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665; ISK5; LEKT1; LEKTI; LETK1; LETKI; lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor; Netherton syndrome; NETS; NS; serine peptidase inhibitor, Kazal type 5; serine protease inhibitor Kazal-type 5; serine protease inhibitor, Kazal type 5; SPINK5; VAKT1; VAKTI
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 11005
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid