Invitrogen™ SPDL1 Monoclonal Antibody (K06314_12F11), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA555842

Product Code. 30197146

Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Specifications

• Antigen: SPDL1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: Q96EA4
• Gene Symbols: SPDL1
• Immunogen: Human SPDL1 peptide (proprietary range information).
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: K06314_12F11
• Conjugate: Unconjugated
• Gene: SPDL1
• Gene Alias: 1700018I02Rik; 2600001J17Rik; 2810049B11Rik; AA409762; arsenite-related gene 1 protein; Ccdc99; coiled-coil domain containing 99; coiled-coil domain-containing protein 99; coiled-coil domain-containing protein 99 {ECO:0000255; HAMAP-Rule:MF_03041}; hSpindly; protein Spindly; RGD1306908; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255; spindle apparatus coiled-coil protein 1; spindly homolog
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 54908
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid