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Tocris Bioscience™ SB 590885
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Quantity:
10 mg
Unit Size:
10mg
Description
Potent B-Raf inhibitor (Kd = 0.3 nM). Selective for B-Raf against 46 other kinases (Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-RafV600E.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 453.54 |
| Purity | >98% |
| Molecular Weight (g/mol) | 453.55 |
| Chemical Name or Material | SB 590885 |
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