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Tocris Bioscience™ SB 218078
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Product Code. 18054732
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18054732 1 mg 1mg
18025192 10 mg 10mg
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Product Code. 18054732 Supplier Tocris Bioscience™ Supplier No. 2560/1

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Description

Chk1 inhibitor

Inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively). Abrogates G2 cell cycle arrest caused by γ-irradiation and topoisomerase I inhibition. Potentiates cytotoxicity of DNA-damaging drugs, enhancing the efficacy of some chemotherapeutics.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 135897-06-2
Molecular Formula C24H15N3O3

Specifications

Quantity 1 mg
Formula Weight 393.39
Purity >98%
Molecular Weight (g/mol) 393.402
Chemical Name or Material SB 218078
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