S100A10 Mouse anti-Human, Clone: 1B3F9, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16807915	Proteintech 66227-1-IG-20UL	20 μL
16897905	Proteintech 66227-1-IG-150UL	150 μL

Description

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

Specifications

• Antigen: S100A10
• Concentration: 1.72 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: 42C, ANX2L, ANX2LG, Ca[1], CAL1L, Calpactin 1 light chain, Calpactin I light chain, Cellular ligand of annexin II, CLP11, GP11, p10, p10 protein, P11, Protein S100 A10, S100A10
• Gene Symbols: S100A10
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1B3F9
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P60903
• Gene ID (Entrez): 6281
• Immunogen: S100A10 Fusion Protein Ag23596
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: S100A10