Pyruvate Carboxylase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16876244	Proteintech 16588-1-AP-20UL	20 μL
16866244	Proteintech 16588-1-AP-150UL	150 μL

Description

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.

Specifications

• Antigen: Pyruvate Carboxylase
• Applications: Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P11498, P52873, Q05920
• Gene ID (Entrez): 18517, 25104, 5091
• Immunogen: Pyruvate Carboxylase Fusion Protein Ag8857
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PC

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: PC, PCB, pyruvate Carboxylase, Pyruvic carboxylase
• Gene Symbols: Pc
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody