Pyruvate Carboxylase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16588-1-AP-20UL

Product Code. 16876244

Description

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.

Specifications

• Antigen: Pyruvate Carboxylase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PC
• Gene Alias: PC, PCB, pyruvate Carboxylase, Pyruvic carboxylase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18517, 25104, 5091
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11498, P52873, Q05920
• Gene Symbols: Pc
• Immunogen: Pyruvate Carboxylase Fusion Protein Ag8857
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG