PR Mouse anti-Human, Clone: 3D1D12, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16898045	Proteintech 66300-1-IG-20UL	20 μL
16888045	Proteintech 66300-1-IG-150UL	150 μL

Description

The progesterone receptor is a member of the Steroid Hormone Receptor Superfamily. It exists in two distinct isoforms in human cells. PR-B is the transcriptionally active form and is responsible for activating genes for the maintainence of the endometrium, maintece of pregcy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. Phospholabeling studies have shown that PR is phosphorylated in at least 9 different locations in response to progestins, which suggests that PR affects many different cellular pathways.

Specifications

• Antigen: PR
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: NR3C3, PGR, PR, progesterone receptor
• Gene Symbols: PGR
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 3D1D12
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P06401
• Gene ID (Entrez): 5241
• Immunogen: PR Fusion Protein Ag22992
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PGR