Invitrogen™ PLSCR1 Recombinant Rabbit Monoclonal Antibody (24GB1550)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557581

Product Code. 30274905

Beskrivning

PLSCR1 Recombinant Monoclonal Antibody for Western Blot, Flow

The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodelling and surface exposure of phosphatidylserine in injured or apoptotic cells, which leads to cell death. Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways. EGF stilmulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, which allows it to interact with Shc, and thereby connecting Src kinase activation to stimulation of the EGF receptor.

Specifikationer

• Antigen: PLSCR1
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: PLSCR1
• Gene Alias: ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; Plscr1; Tra1; Tra1a; Tra1b; transplantability-associated protein 1; Tras1; Tras2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117540, 22038, 5359
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB1550
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O15162, P58195, Q9JJ00
• Gene Symbols: PLSCR1
• Immunogen: A synthesized peptide derived from human Scramblase 1 (aa 20-55).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG