Invitrogen™ Phospho-KSR1 (Ser392) Recombinant Rabbit Monoclonal Antibody (KSR1S392-3A4), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
17186878	Invitrogen™ MA537292	10 Tests
17136608	Invitrogen™ MA537017	100 Tests

Description

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [UniProt]

Specifications

• Antigen: Phospho-KSR1 (Ser392)
• Applications: Flow Cytometry
• Conjugate: PE
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q61097, Q8IVT5
• Gene ID (Entrez): 16706, 8844
• Immunogen: A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1.
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Gene: KSR1

• Clone: KSR1S392-3A4
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2
• Gene Symbols: KSR1
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody