Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
17106838	Invitrogen™ MA537244	10 Tests
17146528	Invitrogen™ MA536938	100 Tests

Description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

• Antigen: Phospho-4EBP1 (Thr37, Thr46)
• Applications: Flow Cytometry
• Conjugate: APC
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q13541, Q60876, Q62622
• Gene ID (Entrez): 116636, 13685, 1978
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Gene: EIF4EBP1

• Clone: 4EB1T37T46-A5
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
• Gene Symbols: EIF4EBP1
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody