missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyrroles
  7. PHA 665752, Tocris Bioscience™

PHA 665752, Tocris Bioscience™

Catalog Number p-4784281
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
477575-56-7
C32H34Cl2N4O4S
641.608
OYONTEXKYJZFHA-SSHUPFPWSA-N
unii-0vxu5t5r3j, 2r-1-5-z-5-2,6-dichlorophenyl methyl sulfonyl-1,2-dihydro-2-oxo-3h-indol-3-ylidene methyl-2,4-dimethyl-1h-pyrrol-3-yl carbonyl-2-1-pyrrolidinylmethyl pyrrolidine, 0vxu5t5r3j, r,z-5-2,6-dichlorobenzylsulfonyl-3-3,5-dimethyl-4-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylene indolin-2-one, pha-665752 hydrate, 3z-5-2,6-dichlorophenyl methanesulfonyl-3-3,5-dimethyl-4-2r-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylidene-1h-indol-2-one, 3z-5-2,6-dichlorophenyl methylsulfonyl-3-3,5-dimethyl-4-2r-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylidene-1h-indol-2-one, r,z-5-2,6-dichlorobenzyl sulfonyl-3-3,5-dimethyl-4-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylene indolin-2-one, 3z-5-2,6-dichlorophenyl methyl sulfonyl-3-3,5-dimethyl-4-2r-2-1-pyrrolidinylmethyl-1-pyrrolidinyl carbonyl-1h-pyrrol-2-yl methylene-1,3-dihydro-2h-indol-2-one hydrate, d00tbd
10461815
(3Z)-5-[(2,6-dichlorophenyl)methylsulfonyl]-3-[[3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl]methylidene]-1H-indol-2-one
CC1=C(NC(=C1C(=O)N2CCCC2CN3CCCC3)C)C=C4C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O
This item is not returnable. View return policy
477575-56-7
C32H34Cl2N4O4S
641.608
OYONTEXKYJZFHA-SSHUPFPWSA-N
unii-0vxu5t5r3j, 2r-1-5-z-5-2,6-dichlorophenyl methyl sulfonyl-1,2-dihydro-2-oxo-3h-indol-3-ylidene methyl-2,4-dimethyl-1h-pyrrol-3-yl carbonyl-2-1-pyrrolidinylmethyl pyrrolidine, 0vxu5t5r3j, r,z-5-2,6-dichlorobenzylsulfonyl-3-3,5-dimethyl-4-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylene indolin-2-one, pha-665752 hydrate, 3z-5-2,6-dichlorophenyl methanesulfonyl-3-3,5-dimethyl-4-2r-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylidene-1h-indol-2-one, 3z-5-2,6-dichlorophenyl methylsulfonyl-3-3,5-dimethyl-4-2r-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylidene-1h-indol-2-one, r,z-5-2,6-dichlorobenzyl sulfonyl-3-3,5-dimethyl-4-2-pyrrolidin-1-ylmethyl pyrrolidine-1-carbonyl-1h-pyrrol-2-yl methylene indolin-2-one, 3z-5-2,6-dichlorophenyl methyl sulfonyl-3-3,5-dimethyl-4-2r-2-1-pyrrolidinylmethyl-1-pyrrolidinyl carbonyl-1h-pyrrol-2-yl methylene-1,3-dihydro-2h-indol-2-one hydrate, d00tbd
10461815
(3Z)-5-[(2,6-dichlorophenyl)methylsulfonyl]-3-[[3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl]methylidene]-1H-indol-2-one
CC1=C(NC(=C1C(=O)N2CCCC2CN3CCCC3)C)C=C4C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O

Description

Potent and selective MET inhibitor

Potent, selective and ATP-competitive inhibitor of MET kinase (IC50 values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk-1, c-abl, FGFR1, EGFR and c-src respectively and > 10000 nM for IGF-IR, PDGFR, AURORA2, PKA, PKBα, p38α, MK2 and MK3). Antitumor agent; inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
Quantity 10 mg
Formula Weight 641.61
Percent Purity >98%
Chemical Name or Material PHA 665752
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.

Cancel missing translation for 'submit'