PDX1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Produktkode	Brand	Quantity
16810585	Proteintech 20989-1-AP-20UL	20 μL
16800585	Proteintech 20989-1-AP-150UL	150 μL

Description

PDX1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.

Specifications

• Antigen: PDX1
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human
• Gene Accession No.: P52945, P52946
• Gene ID (Entrez): 18609, 3651
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PDX1

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Glucose sensitive factor, GSF, IDX 1, Insulin promoter factor 1, Insulin upstream factor 1, IPF 1, IPF1, Islet/duodenum homeobox 1, IUF 1, IUF1, MODY4, PDX 1, PDX1, STF 1
• Gene Symbols: PDX1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody