PDE6A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16850825	Proteintech 21200-1-AP-20UL	20 μL
16840825	Proteintech 21200-1-AP-150UL	150 μL

Description

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Specifications

• Antigen: PDE6A
• Applications: Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: P16499, P27664
• Gene ID (Entrez): 225600, 307401, 5145
• Immunogen: PDE6A Fusion Protein Ag15562
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PDE6A

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CGPR A, GMP PDE alpha, PDE V B1, PDE6 alpha, PDE6A, PDEA
• Gene Symbols: PDE6A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody