PDE6A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21200-1-AP-20UL

Product Code. 16850825

Description

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Specifications

• Antigen: PDE6A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE6A
• Gene Alias: CGPR A, GMP PDE alpha, PDE V B1, PDE6 alpha, PDE6A, PDEA
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 225600, 307401, 5145
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P16499, P27664
• Gene Symbols: PDE6A
• Immunogen: PDE6A Fusion Protein Ag15562
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Mouse, Human
• Product Type: Antibody
• Isotype: IgG