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DiscoverX PathHunter™ IL17RA/IL17RC Dimerization Bioassay Kit

Product Code. 17384189
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
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17384189 200 dp (2 x 96-well) 1 set
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Product Code. 17384189 Supplier DiscoverX Supplier No. 930999Y300053

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Description

The PathHunter™ IL17RA/IL17RC Dimerization Bioassay Kit measures ligand-induced dimerization of IL17RA/IL17RC. Bioassay kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ IL17RA/IL17RC Dimerization Bioassay kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This bioassay assesses ligand (e.g. IL-17) induced dimerization of IL17RA/IL17RC receptors. This product uses EFC technology. The cell line included overexpresses IL17RC target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL17RA/IL17RC , detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.

Specifications

Assay Entry Dimerization
For Use With (Application) Assay-Ready Bioassay Kits
Quantity 200 dp (2 x 96-well)
Target Entry IL17RA/IL17RC
Cell Line U2OS
Target IL17RA/IL17RC
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