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DiscoverX PathHunter™ eXpress TAAR5 CHO-K1 β-Arrestin Orphan GPCR Assay

Product Code. 17333709
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17333709

Brand: DiscoverX 930718E2CP1M

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This item is not returnable. View return policy

Description

The PathHunter™ eXpress TAAR5 CHO-K1 β-Arrestin Orphan GPCR Assay measures TAAR5 (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ TAAR5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. methylamines) based activation of TAAR5 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged TAAR5 and EA-tagged β-Arrestin 2. Activation of TAAR5 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry GPCR
For Use With (Application) Assay-Ready eXpress Kits
Quantity 200 dp (2 x 96-well)
Target Entry TAAR5
Cell Line CHO-K1
Target TAAR5
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