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DiscoverX PathHunter™ eXpress NPSR1b U2OS β-Arrestin GPCR Assay

Product Code. 17373849
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
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Product Code. Quantity unitSize
17373849 200 dp (2 x 96-well) 1 set
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Product Code. 17373849 Supplier DiscoverX Supplier No. 930822E3CP0M

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Description

The PathHunter™ eXpress NPSR1b U2OS β-Arrestin GPCR Assay measures NPSR1b (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ NPSR1b β-Arrestin eXpress Kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuropeptide S) based activation of NPSR1b GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged NPSR1b and EA-tagged β-Arrestin 2. Activation of NPSR1b stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry GPCR
For Use With (Application) Assay-Ready eXpress Kits
Quantity 200 dp (2 x 96-well)
Target Entry NPSR1b
Cell Line U2OS
Target NPSR1b
Product Title
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