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DiscoverX PathHunter™ eXpress mGHSR1a CHO-K1 β-Arrestin GPCR Assay

Product Code. 17343519
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
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17343519 1,000 dp (10 x 96-well) 1 set
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Product Code. 17343519 Supplier DiscoverX Supplier No. 930605E2MCP2L

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Description

The PathHunter™ eXpress mGHSR1a CHO-K1 β-Arrestin GPCR Assay measures mGHSR1a (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates. Mouse version.

The PathHunter™ mGHSR1a β-Arrestin eXpress Kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. grehlin) based activation of mGHSR1a GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged mGHSR1a and EA-tagged β-Arrestin 2. Activation of mGHSR1a stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein.

Specifications

Assay Entry GPCR
For Use With (Application) Assay-Ready eXpress Kits
Quantity 1,000 dp (10 x 96-well)
Target Entry mGHSR1a
Cell Line CHO-K1
Target mGHSR1a
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