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DiscoverX PathHunter™ eXpress IL6RA/IL6ST Dimerization Assay

Product Code. 17304299
Encompass
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
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Product Code. 17304299

Brand: DiscoverX 931045E3CP5L

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This item is not returnable. View return policy

Description

The PathHunter™ eXpress IL6RA/IL6ST Dimerization Assay measures ligand-induced dimerization of IL6RA/IL6ST . eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ IL6RA/IL6ST Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-6) induced dimerization of IL6RA/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside IL6RA target protein fused to EA. Upon ligand-induced dimerization of IL6RA/IL6ST, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry IL6RA/IL6ST Dimerization
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist IL-6
Quantity 1,000 dp (10 x 96-well)
Target Entry IL6RA/IL6ST
Cell Line U2OS
Target IL6RA/IL6ST
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