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DiscoverX PathHunter™ eXpress IL2RB/IL2RG/IL2RA Dimerization Assay
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
Description
The PathHunter™ IL2RB/IL2RG/IL2RA Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-2) induced dimerization of IL2RB/IL2RG/IL2RA receptors. This product uses EFC technology. The cell line included overexpresses IL2RB target protein fused to PK alongside IL2RG target protein fused to EA and untagged ILR2A. Upon ligand-induced dimerization of IL2RB/IL2RG/IL2RA , detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Specifications
Specifications
| Assay Entry | IL2RB/IL2RG/IL2RA Dimerization |
| For Use With (Application) | Assay-Ready eXpress Kits |
| Primary Agonist | IL-2 |
| Quantity | 200 dp (2 x 96-well) |
| Target Entry | IL2RB/IL2RG/IL2RA |
| Cell Line | U2OS |
| Target | IL2RB/IL2RG/IL2RA |
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