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DiscoverX PathHunter™ eXpress GHSR1a U2OS β-Arrestin-1 GPCR Assay

Product Code. 17332819
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17332819

Brand: DiscoverX 930242E3CP5M

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This item is not returnable. View return policy

Description

The PathHunter™ eXpress GHSR1a U2OS β-Arrestin-1 GPCR Assay measures GHSR1a (ARR1) (GPCR) activity via recruitment of β-Arrestin-1. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ GHSR1a (ARR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ghrelin) based activation of GHSR1a GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged GHSR1a and EA-tagged β-Arrestin-1. Activation of GHSR1a stimulates the recruitment of β-Arrestin-1 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry GPCR
For Use With (Application) Assay-Ready eXpress Kits
Quantity 200 dp (2 x 96-well)
Target Entry GHSR1a (ARR1)
Cell Line U2OS
Target GHSR1a (ARR1)
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