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DiscoverX PathHunter™ eXpress CDC25A Degradation Assay

Product Code. 17333789
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17333789

Brand: DiscoverX 930765E3CP0M

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This item is not returnable. View return policy

Description

The PathHunter™ eXpress CDC25A Degradation Assay measures pathway activation-induced degradation of CDC25A target protein. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ eXpress CDC25A Degradation Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting the cell cycle checkpoint pathway. This kit enables detection of levels of CDC25a, allowing for assessment of CHK-1-activation-induced CDC25a degradation. This product uses EFC technology. The cell line included overexpresses CDC25a target protein fused to PL. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of CDC25a EFC signal is lost. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry Pathway
For Use With (Application) Assay-Ready eXpress Kits
Format 200 dp (2 x 96-well)
Quantity 200 dp (2 x 96-well)
Target Entry CDC25A
Target CDC25A
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