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DiscoverX PathHunter™ CHO-K1 MRGPRX2 Bioassay Kit

Product Code. 17302959
Encompass
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17302959

Brand: DiscoverX 930309Y200144

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This item is not returnable. View return policy

Description

The PathHunter™ CHO-K1 MRGPRX2 Bioassay Kit measures MRGPRX2 activity via detection of β-Arrestin recruitment. Bioassay kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ CHO-K1 MRGPRX2 Bioassay Kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay asseses ligand (e.g. Cortistatin 14) based on activation of MRGPRX2 GPCR activity via detection of β-Arrestin recruitment. The included cell line overexpresses ProLink-tagged MRGPRX2 and EA-tagged . Activation of MRGPRX2 stimulates the recruitment of and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.

Specifications

Assay Entry β-Arrestin recruitment
For Use With (Application) Assay-Ready Bioassay Kits
Quantity 1,000 dp (10 x 96-well)
Cell Line CHO-K1
Target MRGPRX2
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