PADI2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16819633	Proteintech 12110-1-AP-20UL	20 μL
16809633	Proteintech 12110-1-AP-150UL	150 μL

Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Specifications

• Antigen: PADI2
• Applications: Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: P20717, Q08642, Q9Y2J8
• Gene ID (Entrez): 11240, 18600, 29511
• Immunogen: PADI2 Fusion Protein Ag2755
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PADI2

• Concentration: 0.22 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: KIAA0994, PAD H19, PAD2, PADI2, PDI2, Peptidylarginine deiminase II
• Gene Symbols: Padi2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody