p130Cas Ab-1 Mouse Monoclonal Antibody, Epredia™

Take advantage of a quality product that delivers accurate results with the Epredia™ p130^Cas Ab-1, Mouse Monoclonal Antibody.

Brand:  Epredia MS-855-P1

Product Code. 12692447

Description

The p130^Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130^Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130^Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130^Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Host Species: Mouse

Clone: CAS-14; same as 35B-1A4

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human p130^Cas protein

Molecular Weight: 130kDa

Positive Control: MCF-7 Cells, HUVEC cells, Tonsil or breast CA

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: p130superscriptCassuperscript Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Purification Method: MCF-7 cells, HUVEC cells, tonsil or breast CA
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: CAS-14; same as 35B-1A4
• Conjugate: Unconjugated
• Immunogen: Recombinant human p130superscriptCassuperscript protein
• Quantity: 500 μL
• Research Discipline: Cell Cycle
• Target Species: Human, Rat
• Isotype: IgG2a κ