NSUN2 Mouse anti-Human, Clone: 2H5A2, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16868585	Proteintech 66580-1-IG-20UL	20 μL
16858585	Proteintech 66580-1-IG-150UL	150 μL

Description

NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).

Specifications

• Antigen: NSUN2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: hTrm4, MISU, NSUN2, SAKI, TRM4
• Gene Symbols: NSUN2
• Isotype: IgG2a
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 2H5A2
• Applications: Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q08J23
• Gene ID (Entrez): 54888
• Immunogen: NSUN2 Fusion Protein Ag14791
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NSUN2