NOX4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16852944	Proteintech 14347-1-AP-20UL	20 μL
16842944	Proteintech 14347-1-AP-150UL	150 μL

Description

Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erytheropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.

Specifications

• Antigen: NOX4
• Applications: Immunocytochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q9JHI8, Q9NPH5
• Gene ID (Entrez): 50490, 50507
• Immunogen: NOX4 Fusion Protein Ag5687
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NOX4

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Kidney oxidase 1, KOX, KOX 1, NADPH oxidase 4, NOX4, Renal NAD(P)H oxidase, RENOX
• Gene Symbols: Nox4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody