NFE2 Mouse anti-Human, Clone: 1D7C8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66436-1-IG-20UL

Product Code. 16818315

Description

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Specifications

• Antigen: NFE2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q16621
• Gene Symbols: NFE2
• Immunogen: NFE2 Fusion Protein Ag1570
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 1D7C8
• Conjugate: Unconjugated
• Gene: NFE2
• Gene Alias: Leucine zipper protein NF E2, NF E2, NFE2, p45, p45 NF E2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 4778
• Content And Storage: -20°C
• Form: Liquid