Naloxone hydrochloride, 98%, Thermo Scientific™

Product Code	Brand	Quantity
15452859	Thermo Scientific Alfa Aesar J60013.MC	100mg
15462859	Thermo Scientific Alfa Aesar J60013.ME	500mg
15442859	Thermo Scientific Alfa Aesar J60013.03	1g

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone

• Naloxone reverses characteristic opioid effects including euphoria, bradycardia, sedation, and respiratory depression

Application

• Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds

• Naloxone is appropriate for use in in vivo and in vitro studies of opioid receptor signaling

Chemical Identifiers

• CAS: 357-08-4
• Molecular Weight (g/mol): 363.838
• InChI Key: RGPDIGOSVORSAK-STHHAXOLSA-N
• PubChem CID: 5464092
• SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl

• Molecular Formula: C19H22ClNO4
• MDL Number: MFCD00069322
• Synonym: naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
• IUPAC Name: (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride

Specifications

• CAS: 357-08-4
• MDL Number: MFCD00069322
• Synonym: naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
• InChI Key: RGPDIGOSVORSAK-STHHAXOLSA-N
• IUPAC Name: (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
• PubChem CID: 5464092
• Percent Purity: 98%

• Molecular Formula: C19H22ClNO4
• Merck Index: 14,6362
• Solubility Information: Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether
• SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
• Molecular Weight (g/mol): 363.838
• Formula Weight: 363.84
• Chemical Name or Material: Naloxone hydrochloride

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

missing translation for 'einecsNumber' : 206-611-0

missing translation for 'rtecsNumber' : QD2275000

missing translation for 'tsca' : No

missing translation for 'storageNote' : 2° to 8°C

Recommended Storage : Keep cold

RUO – Research Use Only