Naloxone hydrochloride, 98%, Thermo Scientific™

Naloxone hydrochloride, CAS # 357-08-4, is involved in the blockade of the mu-opioid receptor and removal of other compounds from the receptor site.

Brand:  Thermo Scientific Alfa Aesar J60013.ME

Product Code. 15462859

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone

• Naloxone reverses characteristic opioid effects including euphoria, bradycardia, sedation, and respiratory depression

Application

• Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds

• Naloxone is appropriate for use in in vivo and in vitro studies of opioid receptor signaling

Chemical Identifiers

• CAS: 357-08-4
• Molecular Weight (g/mol): 363.838
• InChI Key: RGPDIGOSVORSAK-STHHAXOLSA-N
• PubChem CID: 5464092
• SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl

• Molecular Formula: C19H22ClNO4
• MDL Number: MFCD00069322
• Synonym: naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
• IUPAC Name: (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride

Specifications

• CAS: 357-08-4
• MDL Number: MFCD00069322
• Merck Index: 14,6362
• Solubility Information: Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether
• SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
• Molecular Weight (g/mol): 363.838
• Formula Weight: 363.84
• Chemical Name or Material: Naloxone hydrochloride

• Molecular Formula: C19H22ClNO4
• Quantity: 500mg
• Synonym: naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
• InChI Key: RGPDIGOSVORSAK-STHHAXOLSA-N
• IUPAC Name: (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
• PubChem CID: 5464092
• Percent Purity: 98%