Invitrogen™ N4BP1 Recombinant Rabbit Monoclonal Antibody (24GB120)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275452	Invitrogen™ MA557109	100 μL
30276612	Invitrogen™ MA557110	20 μL

Description

N4BP1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

• Antigen: N4BP1
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse, Rat
• Gene: N4BP1
• Gene Alias: AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179
• Gene Symbols: N4BP1
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: 24GB120
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6A037
• Gene ID (Entrez): 291921, 80750
• Immunogen: A synthesized peptide derived from Mouse N4BP1 (aa 286-484).
• Product Type: Antibody