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Invitrogen™ Myc Tag Monoclonal Antibody, HRP

Product Code. 10403212
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10403212 50 μL Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10403212 Supplier Invitrogen™ Supplier No. R95125

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

NOTE: R951-25 was previously sold under product #46-0709. When re-ordering, please use #R951-25. This antibody recognizes amino acid sequence: Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-. This product contains enough material for 25 Western blots. Western blot against 500 ng of recombinant protein gave a strong signal using chemiluminescent or alkaline phosphatase detection reagents. For Western blot, dilute in PBS containing 0.05% Tween-20 and 5% nonfat, dry milk (PBSTM).

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Myc Tag
Applications ELISA, Western Blot
Classification Monoclonal
Conjugate HRP
Formulation PBS with no preservative
Gene MYC
Gene Accession No. P01106
Gene Alias 46-0603; AU016757; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; Niard; Nird; Proto-oncogene c-Myc; R95025; R950-25; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols MYC
Host Species Mouse
Immunogen c-Myc synthetic peptide: Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-.
Purification Method Purified
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4609
Target Species Tag
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Tag
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