Invitrogen™ MSRA Polyclonal Antibody

Rabbit Polyclonal Antibody

Código de producto	Marca	Quantity
17780684	Invitrogen™ PA5119282	200 μL
17723164	Invitrogen™ PA5121764	20 μL

Descripción

MSRA Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.

Especificaciones

• Antigen: MSRA
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Rat, Pig
• Gene: Msra
• Gene Alias: 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
• Gene Symbols: Msra
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.5 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q923M1, Q9UJ68
• Gene ID (Entrez): 100152960, 29447, 4482
• Immunogen: Recombinant protein Methionine Sulfoxide Reductase A. The antigen corresponds to amino acid range 27-235 of the target protein.
• Product Type: Antibody