Invitrogen™ MSRA Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5121764

Product Code. 17723164

Description

MSRA Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.

Specifications

• Antigen: MSRA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Msra
• Gene Alias: 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100152960, 29447, 4482
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q923M1, Q9UJ68
• Gene Symbols: Msra
• Immunogen: Recombinant protein Methionine Sulfoxide Reductase A. The antigen corresponds to amino acid range 27-235 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Rat
• Product Type: Antibody
• Isotype: IgG